… system to evaluate tumor–stromal cell interaction under hypoxia. Using this system, we
analyzed whether hypoxia enhances the invasive activity of pancreatic cancer cells, while also …

… tumor-stromal interaction under hypoxia enhances the invasiveness of pancreatic cancer
cells through hepatocyte … the activation of the HGF/c-Met pathway.18 To date, no studies have …

… We have revealed that tumor–stromal cell interaction under hypoxia increases the
invasiveness of pancreatic cancer cells through the HGF/c-Met pathway ( 21 ) and therefore …

… binding sites for transcription factors, including hypoxia-inducible … the invasive growth
program, in which cancer cells acquire the ability to disrupt cell-to-cell interactions, migrate through …

… with enhanced invasion of pancreatic cancer cells with only high … hypoxic environment in
pancreatic cancers and limits cancer … -stroma interactive loop exists and facilitates tumor growth …

… induced the expression and secretion of HGF in PSC via transcription … of pancreatic cancer
cells to EGFR inhibitor in a KRAS-independent manner by activating the PI3K-AKT pathway. …

… hypoxia has on the ability of pancreatic cancer cells to invade and metastasize. Hypoxia
activates signaling pathways in both cell-… -invasive interactions between cancer and stromal cells…

… is the hepatocyte growth factor (HGF)/c-MET pathway. HGF … the invasiveness of a pancreatic
cancer cell line (PK8) that … from fibroblast cell line (MRC5) under hypoxic conditions; …

… HGF and tumor stromal cells Solid tumors are not just a mass of neoplastic … the invasiveness
of pancreatic cancer cells through the hepatocyte growth factor/ c-Met pathway. Int. J…